Endocrine Abstracts

Background: Hyponatremia is the most common electrolyte disorder in hospitalized patients with pneumonia. Different studies have shown an association of admission hyponatremia and worse in-hospital outcome, but no data are available about the impact of hyponatremia at discharge on outcome.Material and methods: Data from a double-blind randomized study including 725 patients hospitalized with community-acquired pneumonia were analyzed. The primary aim of ...

Background: The main challenge in the diagnosis of arginine vasopressin deficiency (AVP-deficiency, formerly known as central diabetes insipidus), is its distinction against primary polydipsia. Hypertonic saline stimulated copeptin showed a high diagnostic accuracy of 97% in distinguishing between AVP-deficiency and primary polydipsia (Fenske W, Refardt J, NEJM 2018), but comprises discomfort for patients and requires close sodium monitoring. Arginine stimulated copeptin showe...